{"id":89270,"date":"2026-05-02T02:47:14","date_gmt":"2026-05-02T02:47:14","guid":{"rendered":"https:\/\/safetyboot4u.co.za\/?post_type=product&#038;p=89270"},"modified":"2026-05-02T20:25:30","modified_gmt":"2026-05-02T20:25:30","slug":"acetonitrile-99-9-for-hplc-gradient-grade-%ef%bf%bd%ef%bf%bd%ef%bf%bd-25l","status":"publish","type":"product","link":"https:\/\/safetyboot4u.co.za\/?product=acetonitrile-99-9-for-hplc-gradient-grade-%ef%bf%bd%ef%bf%bd%ef%bf%bd-25l","title":{"rendered":"Acetonitrile 99.9% for HPLC Gradient Grade \ufffd\ufffd\ufffd 2,5l"},"content":{"rendered":"<p><strong>Acetonitrile 99.9% HPLC \ufffd\ufffd\ufffd Identification of Product<\/strong><br \/> Chemical Code: CHE-A9<br \/> Chemical Name: Acetonitrile<br \/> Chemical Grade: HPLC<br \/> Chemical Formula: CH\ufffd\ufffd\ufffdCN<br \/> Chemical Weight: 41.05 g\/mol<br \/> CAS No: 75-05-8<br \/> Chemical Synonyms: Methyl Cyanide, ACN.<\/p>\n<p><strong>Acetonitrile 99.9% HPLC \ufffd\ufffd\ufffd Hazards Identification<\/strong><br \/> REACH No: 01-2119471307-38-XXXX<br \/> Signal Word: Danger<br \/> Supplemental Hazard Information:<br \/> Additional Hazard Information: This substance contains no components considered to be either persistent, bio-accumulative and toxic (PBT), or very persistent and very bio-accumulative (vPvB) at levels of 0.1% or higher.<\/p>\n<p><strong>Acetonitrile 99.9% HPLC \ufffd\ufffd\ufffd Hazards statements<\/strong><br \/> H225 \ufffd\ufffd\ufffd Highly flammable liquid and vapour.<br \/> H302 + H312 + H332 \ufffd\ufffd\ufffd Harmful if swallowed, in contact with skin or if inhaled.<br \/> H319 \ufffd\ufffd\ufffd Causes serious eye irritation.<\/p>\n<p><strong>Acetonitrile 99.9% HPLC \ufffd\ufffd\ufffd Precautionary statements<\/strong><br \/> P210 \ufffd\ufffd\ufffd Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.<br \/> P280 \ufffd\ufffd\ufffd Wear protective gloves\/ protective clothing.<br \/> P301 + P312 + P330 \ufffd\ufffd\ufffd IF SWALLOWED: Call a POISON CENTER\/doctor if you feel unwell. Rinse mouth.<br \/> P302 + P352 + P312 \ufffd\ufffd\ufffd IF ON SKIN: Wash with plenty of water. Call a POISON CENTER\/doctor if you feel unwell.<br \/> P304 + P340 + P312 \ufffd\ufffd\ufffd IF INHALED: Remove person to fresh air and keep comfortable for breathing. Call a POISON CENTER\/doctor if you feel unwell.<br \/> P305 + P351 + P338 \ufffd\ufffd\ufffd IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.<\/p>\n<p><strong>Acetonitrile 99.9% HPLC \ufffd\ufffd\ufffd Chemical Composition<\/strong><br \/> Chemical Formula: CH\ufffd\ufffd\ufffdCN<br \/> EC No 1272\/2008: 01-2119471307-38-XXXX<\/p>\n<p><strong>Acetonitrile 99.9% HPLC \ufffd\ufffd\ufffd First Aid Measures<\/strong><br \/> General Advice: Consult a physician. Show this safety data sheet to the doctor in attendance.<br \/> If: Inhaled: If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.<br \/> If: Skin Contact: Wash off with soap and plenty of water. Consult a physician.<br \/> If: Eye Contac: Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.<br \/> If: Swallowed: Do NOT induce vomiting. Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.<br \/> Important Symptoms: The most important known symptoms and effects are described in the labelling section.<br \/> Immediate Medical Attention: No Data Available<\/p>\n<p><strong>Firefighting Measures<\/strong><br \/> Extinguishing Media: Use Water spray, Alcohol-resistant foam, Dry chemical or Carbon Dioxide.<br \/> Hazards Arising: Carbon Oxides, Nitrogen Oxides<br \/> Advice for Firefighters: Wear self-contained breathing apparatus for firefighting if necessary.<br \/> Info for Firefighting: Use water spray to cool unopened containers.Accidental Release Measures<br \/> Personal Precautions: Use personal protective equipment.<br \/> Avoid breathing vapours, mist or gas.<br \/> Ensure adequate ventilation.<br \/> Remove all sources of ignition.<br \/> Evacuate personnel to safe areas.<br \/> Beware of vapours accumulating to form explosive concentrations.<br \/> Vapours can accumulate in low areas.<br \/> Enviromental Precautions: Prevent further leakage or spillage if safe to do so.<br \/> Do not let product enter drains.<br \/> Method for Containment: Contain spillage, and then collect with an electrically protected vacuum cleaner or by wet-brushing and place in container for disposal according to local regulations.<\/p>\n<p><strong>Handling and Storage<\/strong><br \/> Personal Precautions: Avoid contact with skin and eyes.<br \/> Avoid inhalation of vapour or mist.<br \/> Keep away from sources of ignition \ufffd\ufffd\ufffd No smoking.<br \/> Take measures to prevent the build up of electrostatic charge.<br \/> Enviromental Precautions: Store in cool place.<br \/> Keep container tightly closed in a dry and well-ventilated place.<br \/> Containers which are opened must be carefully resealed and kept upright to prevent leakage.<br \/> Exposure Controls | Personal Protection<br \/> Derived No Effect Level (DNEL)<br \/> Workers | Application Area | Exposure Routes | Health Effect | Value<br \/> Workers \ufffd\ufffd\ufffd Inhalation \ufffd\ufffd\ufffd Acute local effects \ufffd\ufffd\ufffd 68 mg\/m\ufffd\ufffd<br \/> Workers \ufffd\ufffd\ufffd Inhalation \ufffd\ufffd\ufffd Acute systemic effects \ufffd\ufffd\ufffd 68 mg\/m\ufffd\ufffd<br \/> Workers \ufffd\ufffd\ufffd Skin contact \ufffd\ufffd\ufffd Long-term systemic effects \ufffd\ufffd\ufffd 32.2mg\/kg BW\/d<br \/> Workers \ufffd\ufffd\ufffd Inhalation \ufffd\ufffd\ufffd Long-term local effects \ufffd\ufffd\ufffd 68 mg\/m\ufffd\ufffd<br \/> Workers \ufffd\ufffd\ufffd Inhalation \ufffd\ufffd\ufffd Long-term systemic effects \ufffd\ufffd\ufffd 68 mg\/m\ufffd\ufffd<br \/> Consumers | Application Area | Exposure Routes | Health Effect | Value<br \/> Consumers \ufffd\ufffd\ufffd Inhalation \ufffd\ufffd\ufffd Acute local effects \ufffd\ufffd\ufffd 220 mg\/m\ufffd\ufffd<br \/> Consumers \ufffd\ufffd\ufffd Inhalation \ufffd\ufffd\ufffd Acute systemic effects \ufffd\ufffd\ufffd 22 mg\/m\ufffd\ufffd<br \/> Consumers \ufffd\ufffd\ufffd Inhalation \ufffd\ufffd\ufffd Long-term systemic effects \ufffd\ufffd\ufffd 4.8 mg\/m\ufffd\ufffd<br \/> Predicted No Effect Concentration (PNEC)<br \/> Water \ufffd\ufffd\ufffd 10 mg\/L<br \/> Soil \ufffd\ufffd\ufffd 2.41 mg\/Kg<br \/> Marine water \ufffd\ufffd\ufffd 1 mg\/LFresh water \ufffd\ufffd\ufffd 10 mg\/L<br \/> Fresh water sediment \ufffd\ufffd\ufffd 7.53 mg\/Kg<br \/> Onsite sewage treatment plant \ufffd\ufffd\ufffd 32 mg\/L<br \/> Engineering Controls: Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.<br \/> Eye\/Face Protection: Face shield and safety glasses. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166 (EU).<br \/> Skin Protection: Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove\ufffd\ufffd\ufffds outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89\/686\/EEC and the standard EN 374 derived from it.<br \/> Full contact<br \/> Material: butyl-rubber. Minimum layer thickness: 0,3 mm<br \/> Break through time: 480 min. Material tested: Butoject\ufffd\ufffd<br \/> Splash contact<br \/> Material: butyl-rubber. Minimum layer thickness: 0,3 mm<br \/> Break through time: 480 min. Material tested: Butoject\ufffd\ufffd<br \/> Data source: KCL GmbH, D-36124, Test method: EN 374.<br \/> If used in solution, or mixed with other substances, and under conditions which differ from EN 374, contact the supplier of the CE approved gloves. This recommendation is advisory only and must be evaluated by an industrial hygienist and safety officer familiar with the specific situation of anticipated use by our customers. It should not be construed as offering an approval for any specific use scenario.<br \/> Body Protection: Complete suit protecting against chemicals. Flame retardant anti-static protective clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace.<br \/> Respiratory Protection: Where risk assessment shows air-purifying respirators are appropriate use a full-face particle respirator with multi-purpose combination, type OV\/AG (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU).<\/p>\n<p><strong>Physical and Chemical Properties<\/strong><br \/> Appearance: Clear, Colourless liquid<br \/> Odour: Ether-like<br \/> Odour Threshold: No Data Available<br \/> pH: No Data Available<br \/> Melting Point: Melting point\/range: \ufffd\ufffd\ufffd 48\ufffd\ufffdC (lit).<br \/> Boiling Point: 81 \ufffd\ufffd\ufffd 82\ufffd\ufffdC (lit).<br \/> Flash Point: 6.0\ufffd\ufffdC (closed cup)Evaporation: 5.8<br \/> Flammability: No Data Available<br \/> Upper\/Lower Flammability or Explosive Limits: Upper explosion limit: 16% (V),<br \/> Lower explosion limit: 3% (V).<br \/> Vapour pressure: 98.64 hPa at 20\ufffd\ufffdC,<br \/> Vapour density: 1.42 \ufffd\ufffd\ufffd (Air = 1.0)<br \/> Relative density: 0.786 g\/cm\ufffd\ufffd at 25\ufffd\ufffdC<br \/> Water solubility: Completely Miscible<br \/> Partition Coefficien: log Pow: \ufffd\ufffd\ufffd 0.54 at 25\ufffd\ufffdC<br \/> Auto-ignition Temperature: 524.0\ufffd\ufffdC<br \/> Decomposition Temperature: No Data Available<br \/> Viscosity: No Data Available<br \/> Explosive properties: No Data Available<br \/> Oxidizing properties: No Data Available<br \/> Other Safety Info: Surface tension \ufffd\ufffd\ufffd 29.0 mN\/m at 20.0\ufffd\ufffdC<br \/> Relative vapour density \ufffd\ufffd\ufffd 1.42 \ufffd\ufffd\ufffd (Air = 1.0)<\/p>\n<p><strong>Stability and Reactivity<\/strong><br \/> Reactivity: No Data Available<br \/> Chemical Stability: Stable under recommended storage conditions.<br \/> Possibility of hazardous reactions: No Data Available<br \/> Conditions to Avoid: Heat, flames and sparks.<br \/> Extremes of temperature and direct sunlight.<br \/> Incompatible Materials: Acids, Bases, Oxidizing agents, Reducing agents, Alkali metals<br \/> Hazardous Decomposition Products: Hazardous decomposition products formed under fire conditions \ufffd\ufffd\ufffd Carbon Oxides, Nitrogen Oxides.<\/p>\n<p><strong>Toxicological Information<\/strong><br \/> Acute Toxicity: LD50 Oral \ufffd\ufffd\ufffd Mouse \ufffd\ufffd\ufffd male and female \ufffd\ufffd\ufffd 617 mg\/kg \ufffd\ufffd\ufffd (OECD Test Guideline 401).<br \/> LC50 Inhalation \ufffd\ufffd\ufffd Mouse \ufffd\ufffd\ufffd male and female \ufffd\ufffd\ufffd 4 h \ufffd\ufffd\ufffd 6,022 mg\/l \ufffd\ufffd\ufffd (OECD Test Guideline 403).<br \/> Inhalation: (Regulation (EC) No 1272\/2008, Annex VI)<br \/> LD50 Dermal \ufffd\ufffd\ufffd Rabbit \ufffd\ufffd\ufffd male and female \ufffd\ufffd\ufffd &gt; 2.000 mg\/kg \ufffd\ufffd\ufffd (OECD Test Guideline 402)<br \/> Dermal: (Regulation (EC) No 1272\/2008, Annex VI)Skin Corrosion\/Irritation: Rabbit \ufffd\ufffd\ufffd<br \/> Result: No skin irritation \ufffd\ufffd\ufffd 4 h \ufffd\ufffd\ufffd (OECD Test Guideline 404)<br \/> Serious Eye damage | Eye Irritation: Rabbit<br \/> Result: Eye irritation \ufffd\ufffd\ufffd (OECD Test Guideline 405)<br \/> Cell Mutagenicity: Ames test:<br \/> S. typhimurium \ufffd\ufffd\ufffd Result: negative<br \/> In vitro mammalian cell gene mutation test:<br \/> Chinese hamster ovary cells \ufffd\ufffd\ufffd Result: negative.<br \/> Mutagenicity (mammal cell test): chromosome aberration \ufffd\ufffd\ufffd<br \/> Chinese hamster ovary cells \ufffd\ufffd\ufffd Result: Positive results were obtained in some in vitro tests (National Toxicology Program).<br \/> Sister chromatid exchange assay:<br \/> Chinese hamster ovary cells \ufffd\ufffd\ufffd Result: negative<br \/> Sister chromatid exchange:<br \/> Saccharomyces cerevisiae \ufffd\ufffd\ufffd Result: positive \ufffd\ufffd\ufffd Cytogenetic analysis (ECHA)<br \/> In vitro mammalian cell gene mutation test:<br \/> Mouse lymphoma test \ufffd\ufffd\ufffd Result: negative \ufffd\ufffd\ufffd OECD Test Guideline 474<br \/> Mouse \ufffd\ufffd\ufffd male and female \ufffd\ufffd\ufffd Result: negative<br \/> Carcinogenicity: No evidence of carcinogenicity in animal studies.<br \/> IARC: No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC.<br \/> Reproductive toxicity: Animal testing did not show any effects on fertility.<br \/> Specific Target Organ Toxicity \ufffd\ufffd\ufffd Single Exposure: The substance or mixture is not classified as specific target organ toxicant, single exposure.<br \/> Specific Target Organ Toxicity \ufffd\ufffd\ufffd Repeated Exposure: The substance or mixture is not classified as specific target organ toxicant, repeated exposure.<br \/> Aspiration Hazard: No Data Available<\/p>\n<p><strong>Ecological Information<\/strong><br \/> Ecological Toxicity: Toxicity to fish:<br \/> Flow-through test LC50 \ufffd\ufffd\ufffd Pimephales promelas (fathead minnow) \ufffd\ufffd\ufffd 1.640 mg\/l \ufffd\ufffd\ufffd 96 h \ufffd\ufffd\ufffd Remarks: (ECHA).<br \/> Toxicity to daphnia and other aquatic invertebrates:<br \/> Static test LC50 \ufffd\ufffd\ufffd Artemia salina (Brine shrimp) \ufffd\ufffd\ufffd 400 mg\/l \ufffd\ufffd\ufffd 24 h \ufffd\ufffd\ufffd Remarks: (ECHA).<br \/> Toxicity to algae:<br \/> Static test NOEC \ufffd\ufffd\ufffd Phaeodactylum tricornutum \ufffd\ufffd\ufffd 400 mg\/l \ufffd\ufffd\ufffd 72 h \ufffd\ufffd\ufffd (ISO 10253).<br \/> Static test ErC50 \ufffd\ufffd\ufffd Phaeodactylum tricornutum \ufffd\ufffd\ufffd 9.696 mg\/l \ufffd\ufffd\ufffd 72 h \ufffd\ufffd\ufffd (ISO 10253). Toxicity to bacteria:<br \/> Static test EC50 \ufffd\ufffd\ufffd activated sludge \ufffd\ufffd\ufffd &gt; 1.000 mg\/l \ufffd\ufffd\ufffd 30 min \ufffd\ufffd\ufffd (OECD Test Guideline 209).<br \/> Ecological Persistence and degradability: Biodegradability Result: 70% \ufffd\ufffd\ufffd Readily biodegradable (OECD Test Guideline 301)<br \/> Bioaccumulative Potential: No bio-accumulation is to be expected (log Pow ? 4)<br \/> Mobility in Soil: Not expected to adsorb on soil<br \/> Results of PBT and vPvB Assessment: This substance contains no components considered to be either persistent, bio-accumulative and toxic (PBT), or very persistent and very bio-accumulative (vPvB) at levels of 0.1% or higher.<br \/> Other Adverse Effect: Avoid release to the environment.<br \/> Stability in water:<br \/> Remarks: Hydrolyses slowly<\/p>\n<p><strong>Disposal Considerations<\/strong><br \/> Waste Treatment Methods: Product \ufffd\ufffd\ufffd<br \/> Burn in a chemical incinerator equipped with an afterburner and scrubber but exert extra care in igniting as this material is highly flammable. Offer surplus and non-recyclable solutions to a licensed disposal company.<br \/> Contaminated packaging \ufffd\ufffd\ufffd Dispose of as unused product.<\/p>\n<p><strong>Transport Information<\/strong><br \/> UN Number: ADR\/RID: 1648<br \/> IMDG: 1648<br \/> IATA: 1648<br \/> UN Shipping Hazard: ADR\/RID: Acetonitrile<br \/> IMDG: Acetonitrile<br \/> IATA: Acetonitrile<br \/> Transport Hazard Class: ADR\/RID: 3<br \/> IMDG: 3<br \/> IATA: 3<br \/> Packaging Group: ADR\/RID: II<br \/> IMDG: II<br \/> IATA: II<br \/> Enviromental Hazards: ADR\/RID: no<br \/> IMDG Marine pollutant: no<br \/> IATA: no<br \/> Special Precautions: No Data AvailableRegulatory Information<br \/> Safety, Health and environmental regulations: This safety datasheet complies with the requirements of Regulation (EC) No. 1907\/2006.<br \/> Chemical Safety Assessment: A Chemical Safety Assessment has been carried out for this substance.<br \/> Additional Info: RTECS: AL7700000<br \/> Treat as Cyanide poisoning.<br \/> Always have on hand a Cyanide first-aid kit, together with proper instructions.<br \/> The onset of symptoms is generally delayed pending conversion to Cyanide.<br \/> Nausea, vomiting, diarrhoea, headache, dizziness, rash, cyanosis, excitement, depression, drowsiness, impaired judgment, lack of coordination, stupor and death.<br \/> To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated.<\/p>\n<p><strong>Disclaimer<\/strong><br \/> The information stated above is considered to be correct, but does not claim to be inclusive and shall only be used as a guideline. The information provided by this document is confirmed by our continuous updating of knowledge and adheres to the products appropriate safety precautions. It does not represent any guarantee of the product\ufffd\ufffd\ufffds<br \/> properties. RLS Chemicals and its Associates shall not be held accountable for any damage\ufffd\ufffd\ufffds consequent of handling the above product<\/p>\n<p>Add to Wishlist<\/p>\n<p> Add to Wishlist<\/p>\n","protected":false},"excerpt":{"rendered":"<p><strong>Chemical Folmula:<\/strong> CH3CN<br \/> <strong>Molar Mass:<\/strong> 41.05 g\/mol<br \/> <strong>Melting Point:<\/strong> -48\ufffd\ufffdC<br \/> <strong>Boiling Point:<\/strong> 81-82 \ufffd\ufffdC<br \/> <strong>Ignition Point:<\/strong> 525\ufffd\ufffdC<br \/> <strong>Appearance:<\/strong> Clear, colourless liquid<br \/> <strong>Density @20\ufffd\ufffdC (g\/ml):<\/strong> 0.7822 \ufffd\ufffd\ufffd 0.786 g\/ml<\/p>\n<p>Acetonitrile 99.9% is a high-purity, colorless, volatile liquid widely used as a solvent in high-performance liquid chromatography (HPLC), pharmaceutical manufacturing, and chemical analysis. It is completely miscible with water and most organic solvents, providing excellent elution capabilities and low UV absorbance for precise analytical procedures.<\/p>\n","protected":false},"featured_media":97813,"template":"","meta":{"content-type":""},"product_brand":[],"product_cat":[28878,32321],"product_tag":[19806,49245],"class_list":{"0":"post-89270","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-lab-chemicals","7":"product_cat-lab-chemicals-hplc","8":"product_tag-5l","9":"product_tag-acetonitrile-99-9-for-hplc-gradient-grade--2","11":"first","12":"instock","13":"taxable","14":"shipping-taxable","15":"purchasable","16":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/safetyboot4u.co.za\/index.php?rest_route=\/wp\/v2\/product\/89270","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/safetyboot4u.co.za\/index.php?rest_route=\/wp\/v2\/product"}],"about":[{"href":"https:\/\/safetyboot4u.co.za\/index.php?rest_route=\/wp\/v2\/types\/product"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/safetyboot4u.co.za\/index.php?rest_route=\/wp\/v2\/media\/97813"}],"wp:attachment":[{"href":"https:\/\/safetyboot4u.co.za\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=89270"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/safetyboot4u.co.za\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_brand&post=89270"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/safetyboot4u.co.za\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_cat&post=89270"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/safetyboot4u.co.za\/index.php?rest_route=%2Fwp%2Fv2%2Fproduct_tag&post=89270"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}